Can I bake a cake mix in a single loaf pan? What size and how long?

You can bake cake mix in loaf pans. Grease and flour the bottom only and bake at 325 to 350 for 35 to 55 minutes depending on the pan size. One 9x5 loaf pan will be very full and will bake for 50 minutes +.  You can use two 8x4-inch pans and start checking for doneness at around 35 minutes. Use a toothpick test for doneness. Here are a few recipes to use as guides: Honey-Walnut Pound Cakes, Lemon Pound Cake, and Piña Colada Pound Cakes. Happy baking!